EXPRESSION AND FUNCTION OF TRANSMEMBRANE-4 SUPERFAMILY (TETRASPANIN) PROTEINS IN OSTEOCLASTS: RECIPROCAL ROLES OF TSPAN-5 AND NET-6 DURING OSTEOCLASTOGENESIS

Background: Osteoclasts are bone-resorbing multinuclear polykaryons essential for bone remodeling, formed through cell fusion of mononuclear macrophage/monocyte lineage precursor cells upon stimulation by the RANK/RANKL system.Recent studies have revealed that a family of tetraspanin proteins, such as CD9, is critically involved in the cell fusion/

This article jim beam candy aims to explore the transnational links of activism against racial discrimination in two territories: the United States and Canada.Indeed, although the fights of the leaders of the American civil rights movement as well as the organisations which fought against systemic racism are known throughout the world; black activi

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